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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Introduction

Cancer is the third most common cancer worldwide, and it is the second-leading cause of disability in the United States []. According to the World Health Organization (WHO), the global cancer burden is approximately 1.2 billion deaths annually, which is a staggering sum of global health costs []. The rising incidence of cancer among cancer patients is not only due to the rising cancer prevalence but also because of the rising cancer incidence in developed countries, as seen in Asia, Europe, and the Middle East and Africa [, ]. This rising incidence is primarily due to the increasing number of cancer cases in patients who are newly diagnosed and the high mortality rate. Furthermore, the rising incidence of cancer is also associated with the high morbidity and mortality rates worldwide [, ]. According to the World Health Organization (WHO), the global cancer burden is approximately 1.4 billion deaths annually []. The cancer incidence in the United States is estimated to be nearly 4.5 million, which is about 2.8 times as high as in most developed countries []. However, the rising incidence of cancer in both developed and developing countries is largely due to the high burden of cancer and other diseases [].

The rising incidence of cancer in the United States has led to the need for effective strategies to reduce the incidence and mortality rates []. Several recent studies have demonstrated the efficacy of herbal supplements such as sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra) in preventing the growth of cancer []. Additionally, sildenafil is widely used for the treatment of erectile dysfunction and benign prostatic hyperplasia. However, the effectiveness of herbal supplements for their anti-cancer properties is still controversial [].

The present review aims to explore the efficacy of herbal supplements for the treatment of cancer and related diseases.

Methods

The present review provides a comprehensive review of the efficacy of herbal products for the treatment of cancer and related diseases. The studies included in this review were published between 2015 and 2023, and the review was updated annually in 2023.

Definition

A herbal product is a herbal substance that is used for the treatment of erectile dysfunction, benign prostatic hyperplasia, and other related conditions. The primary use of herbal products for erectile dysfunction is to reduce the risk of a disease. The herbal products are often recommended in combination with other therapies and are sometimes recommended to be taken only as a single treatment, and are sometimes recommended with other treatments, including chemotherapy and radiation therapy, to treat cancer, including lymphoma, certain neuroendocrine disorders, and other diseases.

The term “herbal” refers to the use of any herbal substance to treat a particular condition. The term “herbal medicine” refers to the use of any herbal substance to treat the health condition for which it is intended, and it includes natural supplements, herbal remedies, and other forms of herbal medicine. The term “herbal medicine” also includes the use of natural herbal supplements, herbal teas, and herbal supplements that are derived from plants, roots, and other natural components.

Review Article

According to the current review, the herb products of the Herbal Supplements for Cancer (HSP), such as sildenafil, tadalafil, and vardenafil, have been used for the treatment of cancer, such as cancer of the prostate, bladder, and liver, as well as for other related conditions such as benign prostatic hyperplasia and benign prostate hyperplasia [, ]. In addition, the herbal supplements have been used for the treatment of erectile dysfunction in men [].

According to the present review, the herb products of the Herbal Supplements for Cancer (HSP), such as sildenafil, tadalafil, and vardenafil, have been used for the treatment of cancer, such as cancer of the prostate, bladder, and liver, as well as for other related conditions such as benign prostate hyperplasia and benign prostate hyperplasia []. In addition, the herbal products have been used for the treatment of erectile dysfunction in men [].

As with most drug approvals, the FDA has received approval for several medications, including the erectile dysfunction drug Viagra.

Pfizer Inc. is the company that makes the erectile dysfunction medications, Viagra. The company develops and produces these drugs, with the goal of helping men gain a stronger and longer-lasting erection. However, in recent years, there has been a growing number of people switching to the more expensive ED medications.

In April, the Food and Drug Administration approved the first generic version of Viagra, the generic version of Pfizer's impotence drug, Levitra. In April and June, Viagra will be the only ED drug approved for use in men with high blood pressure.

The FDA approved the drug to treat high blood pressure, which is the most common type of hypertension in the United States. The FDA approved the first generic Viagra drug, the generic drug Levitra, in December 2004. It was also approved to treat a type of erectile dysfunction that affects a large number of men.

The FDA also approved the first generic Levitra drug, the generic version of Viagra, in November 2006. Since then, the pharmaceutical company has been helping men get better erections and keeping that good experience going.

The FDA approved Viagra to treat erectile dysfunction (ED) in men over the age of 18, which is estimated to affect around 25 million men in the United States. ED is a common condition that affects about 20% of American adults.

Viagra is the first drug approved to treat the condition. It works by relaxing the blood vessels in the penis, allowing more blood to flow into the penis when you get sexually excited.

Viagra can help men get an erection by increasing blood flow to the penis and making it easier to have an erection. In fact, many men have used Viagra to treat ED, but many do not have an erection for sexual activity.

Viagra does not cure erectile dysfunction. It only works to improve the blood flow to the penis when you have sexual arousal. Viagra helps to relax the blood vessels in your penis to increase blood flow. This helps to increase blood flow when you are sexually aroused.

When you take Viagra, you do not get an erection just by taking the pill. Instead, you get an erection when you have sexual arousal.

If you are taking medications to help you get an erection, these medications may help you get an erection. These medications include:

Viagra can cause a dangerous drop in blood pressure, leading to dizziness, fainting, and even death.

Taking Viagra can also cause other serious side effects such as chest pain, fainting, and more serious complications.

A dangerous drop in blood pressure can lead to serious heart or liver problems and a higher risk of stroke, especially in men over the age of 65.

People who take nitrates, such as nitroglycerin, may be at an increased risk of heart problems and stroke, especially in older adults or those with pre-existing conditions.

Other dangerous side effects of Viagra include:

People who take certain medications, including:

In rare cases, Viagra can cause a life-threatening allergic reaction to your blood vessels, which may cause a fatal drop in blood pressure. If you are allergic to sildenafil or any of the other ingredients in Viagra, you may have a serious allergic reaction to Viagra. If you have a serious allergic reaction, you should seek medical help right away.

If you experience any of the following symptoms while taking Viagra:

Chest pain or fainting

Fainting or dizziness

Stomach or intestinal cramps

Weakness

Stomach pain

Shortness of breath

Shortness of vision

Swelling of the face, lips, tongue, or throat

Shortness of the breath

Unusual vaginal discharge or itching

Unusual vaginal bleeding or itching

Fainting or fainting

Pain during sexual intercourse

Changes in vision, such as having a color vision problems, or having an erection that lasts longer than four hours

Pale-looking vision or seeing halos around lights

Seizures

Rarely, Viagra can cause a life-threatening allergic reaction to your blood vessels.

A few years ago, the Delhi-based pharmaceutical company Pfizer had announced a price hike on its erectile dysfunction medicine Viagra. This price hike is being referred to as a “price gouging”. It was the result of a study done by the Delhi Medical Association. This study showed that the price of the drug, which is called Viagra, is much lower than the price that men pay in the US. So the Delhi Medical Association, which is the main shareholder in Pfizer, was not involved in the price hike. The study, published in the, looked at data from the last 15 years of the. It found that the price of the drug Viagra in India, which is called sildenafil, was about Rs 1,050 per pill, while the price of the drug Cialis in India was Rs 550 per pill. In the study, the price of the drug Viagra was found to be higher than that of Cialis and also higher than the price of Cialis. Thus, it was revealed that this is a problem for the company. The researchers also found that the price of the drug sildenafil was higher than that of Viagra, which is called viagra. So this is a problem for the company. Pfizer also said it was not involved in the price hike of Viagra. However, other pharmaceutical companies have been involved in this issue. The company is also a major distributor of Viagra.

A few years ago, the Delhi-based drug company Biogen just decided to raise its price of Viagra from Rs 1,100 to Rs 1,200.

The Delhi Medical Association has also claimed that it has raised prices of Viagra in the past.It claimed that in 2010, the company was responsible for the price hike of the drug. In other words, it has been a huge moneymaker. The Delhi Medical Association said that this was the result of the ‘price gouging’. It stated that it has raised the price of the drug from Rs 1,100 to Rs 1,200. In other words, it has raised the price of Viagra from Rs 1,100 to Rs 1,200.

A few years ago, Pfizer announced a price hike on its erectile dysfunction medicine Viagra. This price hike is being referred to as a ‘price gouging’. This study found that the price of the drug, which is called Viagra, is much lower than the price that men pay in the US.

Viagra and Cialis

A few years ago, the Delhi Medical Association has claimed that it has raised prices of Viagra in the past.